SPIROMICS at ATS 2026

The 2026 American Thoracic Society (ATS) International Conference will be held in Orlando, Florida May 15th-20th.  SPIROMICS and SOURCE-related events are listed below. See the full program of events for ATS 2026 here.

Recognition Awards for Scientific Accomplishments

Monday, May 18

2:15pm - 3:45pm EDT: Session G3 W300 (Level III, OCCC West Concourse)

3:23pm EDT: Molecular Phenotyping of Obstructive Lung Diseases - Prescott Woodruff, MD, MPH

SPIROMICS Social

Monday, May 18

3:30pm - 5:30pm EDT at The Pub Orlando

Mid-Day Symposium

Monday, May 18 

12pm-1pm EDT: New Results from the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS) Family of Studies (MD18). 

  • Cell-Free DNA Levels and Tissue Profiles Associated with Severe COPD Exacerbations. Presented by: Mary Elizabeth Richert, MD
  • Early Results from the SOURCE Study. Presented by: Meilan K. Han, MD, MS, ATSF
  • Myocardial Fibrosis in CPFE in the SPIROMICS Heart Failure Study. Presented by: Bharath Venkatesh, PhD
  • Report from the COPDGene-SPIROMICS Multiomics Workshop. Presented by: Prescott Woodruff, MD, MPH

Mini Symposiums

Sunday, May 17 

9:15-11:15am EDT: A Picture Paints a Thousand Words: Imaging Pulmonary Structure and Function (A20) will include a session One-year Progression in Quantitative CT Parameters Predicts Subsequent Lung Function Decline Over 5 Years: The Subpopulations and Intermediate Outcome Measures in COPD Study (Spiromics), presented by Emilia Hermann, MD, MPH. 

9:15-11:15am EDT: Catching Fibrosis in the Act: ILD Screening and ILA (A15) will include a session Proteins Associated with Severity and Mortality in Interstitial Lung Abnormalities, presented by Jonathan Rose, MD, MS. 

9:15-11:15am EDT: COPD Crystal Ball: Life-Course Risk Factors and Advanced Predictive Models (A16). 

  • Significance of Mucus Plugs in Early COPD: An Analysis of the SOURCE Cohort, presented by Sundaresh Ram, MS, PhD
  • The Respiratory Effects of Prematurity Extend Over the Lifespan: Analyses from the SPIROMICS and SOURCE Studies, presented by Brianna Aoyama, MD, MHS

Monday, May 18 

2:15-4:15pm EDT: Decoding Disease: Biomarkers, Phenotypes, and Precision Medicine (B101) will include a session Proteomics of Airway Measures: The SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS), presented by Daniel Guzman, MD, MSE. 

2:15-4:15pm EDT: Where There’s Heat, There’s (Sometimes) Fire: Respiratory Consequences of a Warming World (B97) will include a session on Seasonal Wildfire Smoke Exposure, Circulating Proteomics, and Health Outcomes: A Molecular Epidemiological Study in Spiromics, presented by Yue Feng, PhD. 

Tuesday, May 19 

2:15-4:15pm EDT: Precision Approaches to COPD: Novel Diagnostics, Risk Stratification, and Personalized Treatment (C93) will include a session on Predictors of Recurrent Respiratory Events Among Younger Smokers: Insights from the SOURCE Cohort, presented by Christopher Bosma, MPH. 

Wednesday, May 20 

8:15-10:15am EDT: A mini symposium on Imaging in COPD: Structural Biomarkers, Longitudinal Changes, and Clinical Outcomes (D13). 

  • Mucus Plugging and Its Associations with Mucin Concentrations, Symptoms, Smoking Burden, and Chronic Bronchitis in Early COPD: SOURCE Cohort Analysis, presented by Sundaresh Ram, MS, PhD
  • The Association Between Long-Term Air Pollutant Exposures and Pulmonary Vascular Pruning Among Tobacco-Exposed Individuals with COPD: A Spiromics Analysis, presented by Christopher Bosma, MPH

Poster Sessions

Sunday, May 17 

9:15-11:15am EDT: More Than Inhalers: Determinants of COPD Care and Outcomes (A23) will include a poster on the topic Sleep Inequities Persist Over Time in Heavy Smokers, presented by Aaron Baugh, MD, MS. 

2:15-4:15pm EDT: COPD Biomarkers and Phenotyping: Multi-Omic Insights, AI-Driven Discovery, and Clinical Implications (A101) will include a poster on the topic Glucose, Fructosamine, and Diabetes Status Association with Respiratory Adverse Outcomes Among Current and Former Smokers with COPD, presented by Vickram Tejwani, MD.

Monday, May 18

9:15-11:15am EDT: Smoking Across Modalities and Impacts on the Respiratory System (B26) will include a poster on the topic Characteristics of Acute Respiratory Events Among Younger Adult Ever-Smokers: Insights from the Source Cohort, presented by Shihla Shireen Kanamgode, MD. 

11:30am-1:15pm EDT: Clearing the Airways: Advances in Bronchiectasis and CF Research (B45) will include a poster on the topic Clinical Outcomes Associated with Radiographic Bronchiectasis and Clinical Features in Spiromics, presented by Lynn Sipsey, MD, MBE. 

11:30am-1:15pm EDT: Unraveling the Omic Layers: Translational Insights in Airways Disease (B33) will include a poster on the topic Circulating Metabolomic Signatures of COPD Spirometric Progression in Spiromics and COPDGene, presented by Mohammad Nasirpour, PhD Student. 

2:15-4:15pm EDT: Advancing COPD Diagnosis, Risk Stratification, and Personalized Care: From Biomarkers to Clinical Implementation (B102) will include a poster on the topic Deep Learning-based Detection of Homozygous Alpha-1 Antitrypsin Deficiency from HRCT: A Proof-of-concept Study Across COPDGene, SPIROMICS, and GRADS Cohorts, presented by Vickram Tejwani, MD. 

Tuesday, May 19

From 2:15-4:15pm EDT: Structure Meets Function: Measurements of the Lung (C108) will include a poster on the topic Quantitative Comparison of Pulmonary Perfusion from Paired Non-contrast CT (CT:VQ) and Dual-Energy CT Iodine Maps: A SPIROMICS Analysis, presented by Charles Hatt, PhD. 

From 2:15-4:15pm EDT: The COPD Rubix Cube: ‘Omics and Mechanisms (C101).

  • Chronic Obstructive Pulmonary Disease (COPD) Mucus Pathology Is Associated with Type 2 Inflammation: Multi-omic Evidence from the Spiromics Cohort. Presented by Yingnan Han, MS
  • Discordant Airway Gene Expression of TSLP and Its Specific Receptor Subunit, CRLF2, Links CRLF2 to Mixed Granulocytic Inflammation and Lung Function Decline in SPIROMICS. Presented by Molly Kelly, MD
  • Epigenetic Signatures of Sputum Eosinophils in COPD. Presented by Shuo Cao, PhD
  • Interactions of Leukotriene-B4 and Interleukin-8 Gene Variants and Protein Levels with PI*MZ Heterozygosity Among the COPDGene and SPIROMICS Cohorts. Presented by Vickram Tejwani, MD
  • Lower Airway-to-lung Ratio Links to Neutrophil/macrophage Inflammation and Impaired Mucociliary Clearance in Current Smokers in SPIROMICS. Presented by Stephanie Christenson, MD, MS

Wednesday, May 20

8:15-10:15am EDT: Diving Deeper into COPD Structure and Function (D30).

  • Application of Medical Image Foundation Model for Prediction of Acute Exacerbation in COPD Patients. Presented by Qazaleh Mirsharif, PhD
  • Small Airway-to-Lung Size Ratio Exacerbates Indoor PM2.5 Associated Decline in CT Metrics Associated with Lung Inflammation: A SPIROMICS Air Analysis. Presented by Abhilash Kizhakke Puliyakote, PhD